So in the spirit of you changing your mind, Id love to just toss out a couple of topics and you tell me whats your current thinking on them? Steve LEVITT: It is such a pleasure to be talking today with my good friend Peter Attia, physician, endurance athlete, longevity expert, podcaster. He is of Coptic Egyptian descent. Airplane versus subway? I dont do such silly things anymore. ", "Are We Fighting The Wrong Battle In The Obesity War? And when my daughter was born, I ended up getting a type of medical test that had a finding that no one in their mid-thirties should have. I basically had the worst headache of my life for the next three months. I would be up at five oclock every morning. I lived in Boston. ATTIA: This is actually something thats really interesting. Hes playing the long-game and working hard to maintain the strength and overall good health hell need to continue living an active and fulfilled life even when hes over 100 years old. And when I was applying for my first grant, I went to the senior people around the M.I.T. So I think the whole boxing thing came from an insecurity. Dr. Peter is working hard to keep his body strong and healthy functioning even into old age. All rights reserved. And then, of course, this third piece, which is the emotional resilience and the ability to maintain a tolerance around distress. Dr. Peter Attia. Dr. Peter has an impressive career, but hes an even more impressive person in real life! Six feet versus two feet., And if you could now paint the boundary conditions of that universe with actual data, the next time a virus comes up, we would at least have boundary conditions to say, Oh, this virus looks most like this virus.. So, if we can stop eating a few hours before bedtime, well get better sleep, our bodies will process the glucose we consume, and we can avoid Type 2 diabetes. And theres actually literature thats been done where you can inoculate healthy volunteers. Peter's current diet can simplified into 3 "rules": Time Restricted Feeding Avoid Sugars, High Fructose Corn Syrup & Junk Food No Restriction on Healthy Starches and Vegetables 1) Time Restricted Feeding At the low end, Peter fasts between 14 - 16 hours each day, and at the high end, he fasts between 20 - 22 hours. So how can we combat Type 2 diabetes? He also receives speaking honorariums from organizations, including hospitals and health-related businesses, when he is asked to speak on longevity, metabolic-related topics, athletic performance, and his personal experience working in medicine. Taubes and his cofounder,. So thats called starvation ketosis. I think nicotine is a remarkable molecule. LEVITT: And how much fasting does a person have to do to start getting those benefits? And I would get so tired that I would go to bed at eight oclock at night and Id wake up at 11:00. Thats actually a billion dollar question. My Centenarian Olympics has 18 events in it. ABOUT DR. PETER ATTIA. How do we know if we have Type 2 Diabetes? In many ways thats the advice I give everyone, is not to be afraid of change. For one thing, we can avoid looking at our electronics before bed. ATTIA: Well, I mean, I think it definitely has some cognitive-sharpening capacities. One half of all Americans are on that spectrum. , So how can we combat Type 2 diabetes? What type of a mask really matters? And then you have to have a third project, which is like 75 percent done. ATTIA: No, I think its the hardest job. Ive known Peter for 10 years. It started very early. He explains the evolutionary drive to go from single-cell to multicellular life and unpacks the four different types of cell-based therapies and the problems they are attempting to solve. I think there [are] basically three ways that we can approach dealing with this: One of these is through psychotherapy, pharmacotherapy, and then behavioral therapy, which Im an overwhelming proponent of in particular a type of behavioral therapy called Dialectical Behavioral Therapy or DBT. Dr. Peter Attia. What outcome data are there to show that going above 140 mg/dL in a normal glucose excursion is harmful? But I think there was a very similar insecurity. I think its worth understanding that a little bit. And I ended up having a C.T. Lets talk a little bit about the difference between lifespan and healthspan because theres a really key distinction between them. LEVITT: Yeah, man, I could not agree with those two things more. And I think youve come to appreciate, in recent years, the importance of sleep. ATTIA: Ive come a long way since then, Steve. This mask versus that mask? Now, whether its another SARS coronavirus or an influenza virus or another virus, I dont know. Dr. Peters goal is to reduce those early deaths as much as possible. Peter Attia talks with Steve Levitt about the problem with immortality, what's missing from our Covid response, and why nicotine is underrated. [3], Peter Attia was born on 19 March 1973 in Toronto, Ontario, Canada. And if people say to me, sometimes hey man, Give me one piece of dietary advice, Id be like, Just start reading labels. , a weekly, deep-dive podcast focusing on maximizing longevity by working on physical, cognitive, and emotional health. If you want bread, eat the bread that has no sugar. What was the failure of either policy or medicine that led nobody to be generating that knowledge? But you started out wanting to be a professional boxer. So maybe some combination of those two things would be helpful as a person navigates their way. Marion Nestle notes the Arnold's working relationship with a National Restaurant Association and the National Cattlemen's Beef Association consultant. Both of them are funded by the Arnold Foundation, with substantial ties to animal agriculture industry lobbying. Peter Attia is a physician focusing on the applied science of longevity. And then take a little step further, and you reach neurodegenerative disease, of which Alzheimers disease is far and away the most common and also the most rapidly increasing. And then the evening would be going to the gym for sparring. Why dont we know the dose of fasting? Whats so good about being in ketosis? And finally, the fourth thing that significantly affects our chances of getting Type 2 diabetes is stress. LEVITT: Thats been my reaction exactly, is, the answer to every one of the questions you just posed is completely and totally knowable. In addition to being an accomplished physician, Dr. Peter is also a successful businessman. ATTIA: I mean, look, Steve, that is a million dollar question. So theres this molecule called adenosine. 2 teaspoons (10 mL) every evening with dinner, providing 1600mg EPA and 1,000mg DHA. Comments are welcomed and encouraged. I am a physician focusing on the applied science of longevity. Dr. Peter Attia is the founder of Attia Medical PC. Our lifespan is the amount of time we live, and it is steadily growing longer. No government funds at all, is that right? [6] As his residency drew to a close, Attia joined the consulting firm McKinsey & Company in the Palo Alto office as a member of the Corporate Risk Practice and Healthcare Practice. Yeah, some days its just fun to sit there and laugh and goof off. TheDriveis hosted by Dr. Peter Attia, a Stanford/Johns Hopkins/NIH-trained physician focusing on the applied science of longevity, the extension of human life, and well-being. Physician. Theres days I guess I am. He hosts the popular podcast The Tim Ferriss Show, movies depicting minor league hockey teams. So we evolved this way to instead break down fat, which even under the leanest times, you still had days, if not months worth of energy from, because fat is so energy-dense, and we could turn that fat into a molecule called a ketone. into a difficult position, which is to make very incremental steps in science. It promises to be one of the most important books you'll ever read." Steven D. Levitt, New York Times bestselling author of Freakonomics "In Outlive, Peter Attia explores the science of not just . LEVITT: So, tell me what are your current feelings towards sugar? Dr. Attia is medical doctor who focuses on the science behind living a longer, healthier life. Peter Attia: "I Definitely Lost a Lot of IQ Points That Day" He's been an engineer, a surgeon, a management consultant, and even a boxer. But of course, we live in an environment where natural selection doesnt have the time to make modifications. And tell us about the longest period of time you ever spent in ketosis. So it wasnt one thing, Steve. I definitely had one horrible concussion. By Sydney Bueckert, NASM CPT, CES, FNS, GPT November 23, 2022 Comments requesting medical advice will not be responded to, as I am not legally permitted to practice medicine over the internet. So what are some things we can do to improve our sleep to keep this from happening? LEVITT: I will say that youve taught me a lot and I never told you this before youre one of the few people on the planet whose opinion I trust so completely that when you tell me to do something, no matter how absurd it sounds, I do it. His practice focuses on the applied science of longevity. Post a screenshot of the episode along with your biggest takeaways on Instagram, and make sure to tag Dr. Peter, @peterattiamd, and me, @lewishowes. Peter Attia is among the most brilliant people I've ever met, and he's succeeded in packing a life's worth of insights into this book. And so when I decided to leave, my first thought was actually to go to business school, because I really missed doing quantitative problem-solving. Everything was metabolically broken. LEVITT: So my wife is very upset that I like white bread. Thats the problem that Dr. Peter and other doctors like him are trying to solve. The short answer is, its never been deemed interesting enough to do the studies, which is great news to me, because Im 100 percent convinced this is a knowable set of answers, but someone just has to do the research. His unique spectrum of experience, relentless obsession over details, and ability to translate the cutting edge of science into something the rest of us can use is invaluable., Ive always been fascinated with medicine. And I felt great. You have to have one project which is 95 percent done and turned out well. Theres one disease, which is not really thought of as a disease, but I think of it as a continuum that is the foundation upon which all of those sit. And to me, we want to minimize that gap, right? ATTIA: Yeah, but you have to remember, I mean, the N.I.H. LEVITT: So you love your children with a depth that is rare and I admire. Its one of the three vetted sleep surveys that really can give us insight into your sleep. Dont just listen to people say stuff you agree with. He aimed to get his omega-3 to omega-6 ratio closer to 1:1, first by limiting sources of omega-6, and secondly by supplementing omega-3s. Something about that fructose molecule is really problematic. I think they often get confounded. To improve sleep, Peter Attia takes phosphatidylserine, magnesium and a supplement called Doc Parsley's Sleep Remedy (a company in which Attia invested), comprising of vitamin D, niacin, magnesium (150 mg), and a blend of tryptophan, GABA, phosphatidylserine, theanine, 5-HTP and melatonin. Throughout our lives, we experience different stressors that can cause strain on our mental health. Please be respectful toward other contributors. Can you describe how you approached your undergraduate classes at Stanford? The problem is that we may be living longer, but were living with chronic health conditions that significantly lower our quality of life. Or that we overeat? So the former is one molecule of something called glucose and one of fructose bound together. Im sure anyone who did something at a high level, whether it be playing the piano or doing anything, once theyre so far past their prime, they look back and go, I dont think I appreciated what it took to get there.. And so it might be that its the rigidity of thought that is really the biggest problem. This comment policy is subject to change at any time. So taking a bunch of people who have recovered and asking the question: what does their recovery tell us about their risk of subsequent infection relative to uninfected people? So thats how I ended up at McKinsey. I mean, not even hard to figure out if youre willing to do randomized experiments. And its unfortunate that it was typically packaged with an otherwise horrible set of molecules in cigarettes. This magnesium features what's called an enteric coating to protect it from premature disintegration. Thanks for listening. Learn more at microsoft.com/teams, The Buddha said, To keep the body in good health is a duty otherwise we shall not be able to keep the mind strong and clear. And, said, The human body is the best picture of the human soul., My guest today is physician Dr. Peter Attia. Its about exercising intentionally. Dr. Peter says there are four main ways to do it. After obtaining his medical degree from Stanford University, he was a surgeon at Johns Hopkins and worked at the National Cancer Institute. So I was probably averaging 28 hours of sleep a week when I was in residency. His post can be found here. His practice also focuses on elements such as diet, sleep, exercise, and, physiological aspects that promote Steve, we should have you take the Epworth Sleep Survey. And you would say, Peter, those seem really easy, and youd be right as a 37-year-old stud, but the point is most 60 year olds couldnt do them. . ATTIA: What an obnoxious idiot I was. Mass vaccination would interfere with this a lot. He is the Co-founder and Chief Medical Officer of the fasting app Zero. But the point is, without making these proactive changes, they mightve lived only until 70. Theres an, Tim is an early-stage investor and author of five #1 New York Times bestsellers. And these days I spend virtually no time in nutritional ketosis. pick up the tab to really finish it, because this is a multi-year experiment. Hes one of the most intelligent, curious, compassionate people Ive ever met. Dr. Peter Attia is a physician focusing on the applied science of longevity. To listen ad-free, subscribe to Stitcher Premium. @bariweiss. We care about this. I could basically, within two weeks, turn you into an almost-diabetic by sleep depriving you. Dr. Peter Attia. HOMA-IR and frailty (same study as #3 linked twice); The studies that use OGTT do not establish that glucose variability above 140 mg/dL is important; None show that the high glucose itself is causal or that reducing it via diet will improve outcomes. Saturated fat and dieta postprandial triglyceridemia is associated with cardiovascular disease risk, Why lose weight to prevent covid-19 is an inappropriate and harmful message for health influencers to be sending, Mainstream, popular health gurus peddle ineffective, dangerous, and costly products that degrade physical and financial health, Why I question the objectivity of low-carb pioneers Stephen Phinney and Jeff Volek. We won. ATTIA: I mean, if Im going to be critical, its not what we did in the first moment. If it says its got sugar in it, eat a different version. Lets dive in! I hope you loved this episode as much as I did. So when you contrast living to 70 [and] spending 20 years in misery versus living to 75 with maybe two years in misery, it just doesnt even strike me as a trade-off. . Attia speaks at the Ancestral Health Symposium in 2013, "A Manhattan Project To End The Obesity Epidemic", "Is it what we eat? And the more I learned, frankly, the less I agreed with him. And I hope thats the kind of lesson that I can reinforce, which is: youve got to become a good thinker. Where did this insecurity come from? Dr. Peter is the perfect person to talk to about health and longevity, and Im excited to have him on. Ive known Peter for 10 years. So after college and before grad school. I am responding to this post because: a) Peter's post made it into my message [] Its complicated because there are lots of reagents that go into that type of testing and we dont control the origin of each of those reagents. Because for most people, the last 20 years, especially the last 10 years, are not great, both physically and cognitively. Its a wonderful fuel. And when I was in high school, I became obsessed with him. I want to be able to hop over a three-foot fence. Its the cognitive piece so how well does your brain work as you age? That was painful to watch. LEVITT: And so why? points on that day. When it comes to chronic and life-threatening diseases, Dr. Peter said it comes down to three major things: "So the big three are, in order, atherosclerotic disease so that's vascular disease, meaning heart disease and stroke. And then we talk six months later, thats a distant memory for you. Most organs could use it. Dr. Peter Attia and Dr. Andrew Huberman discuss the best exercises for health and longevity.Dr. ", https://en.wikipedia.org/w/index.php?title=Peter_Attia&oldid=1139971534, Stanford University School of Medicine alumni, Articles with unsourced statements from February 2023, Creative Commons Attribution-ShareAlike License 3.0, This page was last edited on 17 February 2023, at 19:54. LEVITT: No, it was when I worked in consulting. Criticism and skepticism can be far more useful than praise and unflinching belief. Part 1. If you learned something today, please share it with us! And its a finding that basically predicts early onset of cardiovascular disease, which shouldnt have been a surprise to me because the list of men in my family who have died of cardiovascular disease is pretty long. It also impairs senescent cells or more likely impairs the secreting factors that are made by senescent cells. The goal of his website is "to translate the cutting edge of the science of longevity (something roughly 0.01% of people are able to truly understand) into something that . When it comes to chronic and life-threatening diseases, Dr. Peter said it comes down to three major things: So the big three are, in order, atherosclerotic disease so thats vascular disease, meaning heart disease and stroke. The purpose of comments on our site is to expand knowledge, engage in thoughtful discussion, and learn more from readers. We would like it such that, when you die, its really your first encounter with death of any form. Dr. Peter Attia. And I came across this Noam Chomsky documentary. Also, I had a big fight with one of the physicians at Hopkins whos super respected and amazingly prominent. And I now realize in retrospect that was almost assuredly primarily being contributed by the lack of sleep. It showed I had cerebral contusions. So I went, three days and just had water. This is a tragedy. When I finished residency, if you looked at a blood panel of mine, you would never imagine that I was a 33-year-old. But I tried to build a mathematical model to address a problem in the I.C.U. And senescent cells basically send out these really nasty inflammatory signals to other cells that basically age them. Today, we have more medical knowledge than ever before. And youll tell me your latest thing. So they think that you can show them something you havent done when youre done. Fasting turns on a process called autophagy. Comments deemed to be spam or solely promotional in nature will be deleted. So this just reinforced in me that, youre not immortal. document.getElementById( "ak_js_3" ).setAttribute( "value", ( new Date() ).getTime() ); This field is for validation purposes and should be left unchanged. I think I probably spent too many years ignoring things that shouldnt have been ignored. And I think its the perfect model, which is: let the government come in when its been de-risked. How often? For all its successes, mainstream medicine has failed to make much progress against the diseases of aging that kill most people: heart disease, cancer, Alzheimers disease, and type 2 diabetes. Comments containing language or concepts that could be deemed offensive will be deleted. Thats the ultimate goal: To practice medicine and healthy living in such a way that we avoid encountering any kind of death before we have to. And in the meantime, if youre ready to learn how to live to be over 100 and prevent chronic diseases, join me on. Our staff also includes Alison Craiglow, Greg Rippin, and Corinne Wallace; our intern is Emma Tyrrell. When we think of extending our lifespans, we think a lot about our physical health how well our bodies function. When I first met you, that was your obsession, nutrition. I think most people do get a bit of a cognitive jolt from it. And I want you to interrupt me every time you have a question.. [1][2] He is also the first person to make the round-trip swim from Maui and Lanai. And I think a lot of people get there eventually in life, but I would just say, dont be afraid of that type of exploration. So, I think it puts N.I.H. So I know Ive got the time to get better and better. If you learned something today, please share it with us! What does it do for you metabolically? And so I do I think death is a very important part of the carbon cycle. Where did this drive come from? Dr. Attia believes we must replace this outdated framework with a personalized, proactive strategy for longevity, one where we take action now, rather than waiting. After publishing my post Nutrition Science Initiative (NuSI) in retrospect, I received an email from Peter Attia, MD, the former president of NuSI, suggesting that I had gotten aspects of the story wrong due to a lack of additional context.Attia and I spoke twice by phone, and I think he has a point. Which doesnt necessarily undo or undermine the results of that. What things are attributing to bad sleeping patterns. And then I would come home and I had a ritual that I would do 400 pushups every single night in sets of 50s and then go to bed and repeat. LEVITT: All right, so lets talk about your very unusual background. And I think the people who are luckiest and I put myself in that category hit local minima, recognize theyve hit a local minima, but not so much damage has been done that they cant get out of it. Comments including unnecessary profanity will be deleted. LEVITT: And I asked you, Well, how do you know when its time to stop working out? You said, Either when I lose consciousness or when I piss or crap myself, thats when I decide Ive worked out hard enough.. But I still stand by the benefits of nicotine. Our staff also includes Alison Craiglow, Greg Rippin, and Corinne Wallace; our intern is Emma Tyrrell. ATTIA: So a big part of our clumsy response to this is that it couldnt be centrally coordinated. And just to be clear, Im just the guy who started it and who raises the money. I want to be able to pull myself out of a pool where theres a one-foot gap between the water and the curb. Now hes a physician focused on the science of longevity. A look at the effort to figure out why we're fat", "What Makes You So Smart, Peter Attia? When we eat, our bodies naturally raise our temperature its just part of the digestion process. 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